Searching for an Emergency Department Method for Detecting Serious Bacterial Infection in Children

From the AAP:

There is not a pediatrician who has not pondered why we do not have a method for detecting serious bacterial infection (SBI) that is 100% sensitive and specific for predicting who is at high risk and low risk for such infection. While numerous studies have tried to tackle this question and have moved us closer to “diagnostic nirvana,” we are not there yet; although, new diagnostic tools continue to be proposed to get closer to the diagnostic accuracy we all strive for.  For example, new biomarkers are an example of potential diagnostic predictive tools that may, in combination with the usual predictors (clinical exam, white blood count, urinalysis, spinal fluid) make predicting risk for SBI even more accurate.

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