From the Journal of the American Academy of Physician Assistants:
The emergency medicine community has traditionally preferred etomidate for intubation because of its reduced hemodynamic effects, and based on current evidence, it is not possible to say whether etomidate increases mortality compared with other agents. The data do, however, suggest that etomidate is associated with an increased length of hospital stay and with a definite increase in adrenal suppression. Since decreased adrenal function has been demonstrated to increase mortality in patients with sepsis, this remains a concern in the critical care community.
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